Allow rose hips to develop by leaving dead flowers on the plant. The flowers are typically pollinated by insects, or pollinate themselves in some varieties, so there is no need to pollinate by hand unless you are breeding specific plants together. Leave the flowers on the rose plant without cutting them. After they wither, small fruits known as rose hips will develop in their place.
The rose seeds can be planted right away if you have harvested them as late as November, December or January (in Southern California) or early spring after danger of frosts in your area. Place the rose seeds about one-half inch deep in a very light mixture of 50% sterile potting soil and 50% vermiculite. Some rose hybridizers use Sunshine Mix #4. You can use small pots or shallow trays to plant your seeds, whatever works for the space you have, as long as they have good drainage. Nursery flats work well for this. Lightly dust the rose seeds with RooTone or Captan before covering with soil. And then dust the top of the soil again, which will hopefully help to prevent damp-off (a disease which kills young rose seedlings). Amateur rose hybridizers concerned with toxic chemicals may want to periodically spray the seed tray with diluted peroxide and water instead of the more toxic Captan.
Fertilizer: Roses are heavy feeders, and will benefit from a steady supply of nitrogen, phosphorus and potassium. You can provide these nutrients with either liquid or granular fertilizers, at a ratio of approximately 5-8-5. In most cases, regular applications of compost, rotted manure, fish emulsion and seaweed extracts will provide roses with all the nutrients they need. These organic amendments also help to moderate pH imbalances and stimulate beneficial soil life. Other organic amendments favored by rose growers include greensand, black rock phosphate and alfalfa meal.