Please keep in mind that many rose bushes are grafted rose bushes. This means that the bottom part is a hardier rootstock that will withstand cold and heat better than the top and more desired part of the rose bush. Starting a rose bush from cuttings places the new rose bush on its own roots, so it may not be as hardy in cold climates or in extreme heat conditions climates. Being on its own root system can cause the new rose bush to be far less hardy than its mother rose bush.
Selecting a disease-resistant rose is the single most effective way to avoid problems and the need for chemicals. You might start by considering some of the old rose varieties, many of which have natural disease resistance. You can also look to many of the modern roses, which are now being bred for improved disease resistance. Hybrid teas are notoriously disease-prone, and seem to lure every insect pest from miles around. They can be difficult to grow without an arsenal of chemical dusts and sprays.
The next step when you grow roses from cuttings is to use a pencil or metal probe push down into the planting site soil to make a hole that is deep enough to plant the cutting up to about 50 percent of its overall length. Place the cutting that has been dipped into the rooting hormone into this hole. Lightly push the soil in around the cutting to finish the planting. Do the same thing for each cutting keeping them at least eight inches apart. Label each row of rose cuttings with the name of the mother rose bush it was taken from.
There will be disappointments along the way, when many rose seeds fail to germinate, or perhaps they do germinate, only to die several weeks later from damp-off disease. Sometimes a rose seedling will turn out to be as ugly as sin, or very sickly, and you will reluctantly have to throw it away. Other times they will be just ho-hum, or look too much like its parent, and therefore have no value. But, just when you don't expect it, you might discover that one of your rose seedlings turns out to be very special.