Put the rose cuttings directly into water. It’s very important for the rose cuttings to stay hydrated so that they don’t dry out before you plant them. Immediately after you take the rose cuttings, put them in a cup of room temperature water until you’re ready to transfer them. Ideally, you’ll be ready to put them into the soil right after you cut the stems.[3]
The rose seeds can be planted right away if you have harvested them as late as November, December or January (in Southern California) or early spring after danger of frosts in your area. Place the rose seeds about one-half inch deep in a very light mixture of 50% sterile potting soil and 50% vermiculite. Some rose hybridizers use Sunshine Mix #4. You can use small pots or shallow trays to plant your seeds, whatever works for the space you have, as long as they have good drainage. Nursery flats work well for this. Lightly dust the rose seeds with RooTone or Captan before covering with soil. And then dust the top of the soil again, which will hopefully help to prevent damp-off (a disease which kills young rose seedlings). Amateur rose hybridizers concerned with toxic chemicals may want to periodically spray the seed tray with diluted peroxide and water instead of the more toxic Captan.   
When you transplant your roses, be sure to dig a much bigger hole than you think you need (for most types, the planting hole should be about 15 to 18 inches wide), and add plenty of organic matter such as compost or aged manure. This will feed your plant in the years ahead. Some old-timers recommend placing a 4-inch square of gypsum wallboard and a 16-penny nail in the hole to provide calcium and iron, both appreciated by roses.

Choose rose varieties. Did you know there are 13,000 varieties of roses?[1] Some roses grow better in certain regions than in others. When you're choosing what type of rose to grow, take some time to research the specifics of your growing region, then look for roses that have characteristics you find appealing. Take their shape, size, and color into account when choosing varieties to grow. Roses fall into the following categories:

Pests and diseases: Prevention is the best way to avoid pest and disease problems. Start with disease-resistant varieties, keep plants in healthy condition (well fertilized and well watered), maintain good air circulation, keep foliage dry, and remove any diseased foliage or spent flowers. For Japanese beetle grubs, use beneficial nematodes or Milky Spore (Bacillus popilliae). Rose Rx is effective against scale, spidermites and aphids. For more information, see the Pest and Disease Finder.
A special stainless steel screen on the handle of the unit raises up when it is dry. When this happens, it throws the mercury switch which opens the solenoid valve and starts the misting cycle. When this stainless steel screen accumulates enough mist, the weight of the water drops it down again, shutting off the mercury switch, closing the solenoid valve. It needs practically no care or maintenance and can be left on, unattended day and night. This control unit is a very practical instrument which will have a long lifetime of carefree maintenance. There are no clocks to adjust, and it is not affected by water conditions. It works simply on the weight of water. The major benefit of the Mist-a-Matic is to control the misting cycle according to weather conditions. Too much water promotes disease and wastes water. Too little water causes leaves to wilt and failure to root. The Mist-a-Matic distributes the correct amount of water. In hot weather, the unit will turn on more frequently as the water evaporates. In cooler weather, the unit turns on less frequently. For operation, you will need to plug the unit into an electrical outlet. You need to hook it up to a water source with misting nozzles.
Pruning: Dead, weak and sickly stems can lead to disease problems. Pruning these away will increase air circulation to the center of the plant and minimize fungus problems. Pruning also stimulates new growth, and allows you to shape the plant in a pleasing manner. Spent flowers should be removed during the growing season to encourage reblooming. Use a scissor-action pruner for the cleanest cuts.
Fertilizer: Roses are heavy feeders, and will benefit from a steady supply of nitrogen, phosphorus and potassium. You can provide these nutrients with either liquid or granular fertilizers, at a ratio of approximately 5-8-5. In most cases, regular applications of compost, rotted manure, fish emulsion and seaweed extracts will provide roses with all the nutrients they need. These organic amendments also help to moderate pH imbalances and stimulate beneficial soil life. Other organic amendments favored by rose growers include greensand, black rock phosphate and alfalfa meal.