Select two roses that you want to cross-pollenate. The blooms should not be too tight, perhaps about one-half to 3/4 open. Carefully peel off all the petals. The rose stamens inside should look golden yellow and fresh. With sterile tweezers or cuticle scissors, carefully remove all the stamens at the base of the rose hip, so you do not damage the pollen sacs (anthers). Place the rose stamens into separate, clean film canisters, and place the canisters in a dry place, but not in direct sunlight.   
Plant the seeds. Some store-bought seeds can be planted immediately. If you germinated your own seeds as described above, plant them as soon as they begin to sprout. Plant with the sprout pointed downward, as this is the root. Lightly cover them with soil, about 1/4 inch (6 mm) deep. Space seeds at least 2 inches (5 cm) apart to minimize competition.[5]
When pruning, be judicious. If you prune too hard in autumn, plants can be damaged beyond recovery. Instead, wait until spring, when plants begin to leaf out for the new season. (Roses are often not the earliest plants in the garden to respond to spring’s warming temperatures, so be patient.) Give the plant time to show its leaf buds then prune above that level.
NOTE: During my move, I had cut several rose branches and placed them in a grocery paper bag in my garage--only to have forgotten to bring them home for a week. The branches had been in a broiling hot enclosed garage without water, and needless to say, they looked pretty dried out to a crisp. But I didn't want to just toss them out yet (these were the climbing Charisma roses), so I got an empty plastic detergent tub and completely immersed the stems for 2 weeks (no changing water). Then I stuck them into soil and hoped for the best. Well, I got about a 50% survival rate.
Español: cultivar rosas usando semillas, Italiano: Coltivare le Rose Usando i Semi, Português: Cultivar Rosas a Partir da Semente, Русский: вырастить розы из семян, 中文: 用种子种玫瑰, Deutsch: Aus Samenkörnern Rosen ziehen, Français: faire pousser des roses à partir de graines, Nederlands: Rozen kweken uit zaad, Bahasa Indonesia: Menanam Bunga Mawar dari Biji, العربية: زراعة الورود من البذرة, Tiếng Việt: Trồng hoa hồng từ hạt, 日本語: バラを種から育てる, 한국어: 씨앗으로 장미 기르는 방법
I am curious... it seems that you are just supposed to "soak" the cut stems for a week or more in water.... which is mostly what people normally do with cut roses. But whenever I put roses my boyfriend brings me in water, they just fade within a week or so. I'll "feed" the roses with either sugar in the water or with the packet of plant food that comes with them. I'll cut off a small bit at an angle from the bottom of the stem evert day or so. But after a week or so they start wilting and drooping, so at that point I just take them out and hang them upside down to dry.
To start rose bush from cuttings, once the rose cuttings have been taken and brought to the planting site, take out a single cutting and remove the lower leaves only. Make a small slit with a sharp knife on one or two sides of the lower portion of the cutting, not a deep cut but just enough to penetrate the outer layer of the cutting. Dip the lower portion of the cutting into a rooting hormone powder.

There will be disappointments along the way, when many rose seeds fail to germinate, or perhaps they do germinate, only to die several weeks later from damp-off disease. Sometimes a rose seedling will turn out to be as ugly as sin, or very sickly, and you will reluctantly have to throw it away. Other times they will be just ho-hum, or look too much like its parent, and therefore have no value. But, just when you don't expect it, you might discover that one of your rose seedlings turns out to be very special.