The rose seeds can be planted right away if you have harvested them as late as November, December or January (in Southern California) or early spring after danger of frosts in your area. Place the rose seeds about one-half inch deep in a very light mixture of 50% sterile potting soil and 50% vermiculite. Some rose hybridizers use Sunshine Mix #4. You can use small pots or shallow trays to plant your seeds, whatever works for the space you have, as long as they have good drainage. Nursery flats work well for this. Lightly dust the rose seeds with RooTone or Captan before covering with soil. And then dust the top of the soil again, which will hopefully help to prevent damp-off (a disease which kills young rose seedlings). Amateur rose hybridizers concerned with toxic chemicals may want to periodically spray the seed tray with diluted peroxide and water instead of the more toxic Captan.
Pests and diseases: Prevention is the best way to avoid pest and disease problems. Start with disease-resistant varieties, keep plants in healthy condition (well fertilized and well watered), maintain good air circulation, keep foliage dry, and remove any diseased foliage or spent flowers. For Japanese beetle grubs, use beneficial nematodes or Milky Spore (Bacillus popilliae). Rose Rx is effective against scale, spidermites and aphids. For more information, see the Pest and Disease Finder.
Caring for rose bushes is important to their overall health and vigor, especially when it comes to watering. Roses require at least an inch of water weekly throughout their growing season, beginning in spring or following spring planting. While overhead watering is suitable before the onset of new growth, it is often better to water these plants at the soil line using soaker hoses or similar means. Rose bushes are very susceptible to fungal diseases, such as black spot and powdery mildew, especially when their foliage is kept too wet.
There will be disappointments along the way, when many rose seeds fail to germinate, or perhaps they do germinate, only to die several weeks later from damp-off disease. Sometimes a rose seedling will turn out to be as ugly as sin, or very sickly, and you will reluctantly have to throw it away. Other times they will be just ho-hum, or look too much like its parent, and therefore have no value. But, just when you don't expect it, you might discover that one of your rose seedlings turns out to be very special.