Growing roses from seed is certainly not the fastest method of propagating roses, but I can assure you it really is the most rewarding. However, rose hybridizing is surely a lesson in patience, since your success rate can be very small, and it may take several years to reap your rewards. Imagine opening up presents on your birthday or at Christmastime when you were a kid. Well, that's how it feels to see those little rose seedlings open up for the very first time. You never know what you will find inside.
Water. Irrigate roses deeply but infrequently, applying water directly to soil using soaker hoses or drip irrigation. Water needs vary based on weather and soil, so check soil with your finger. Water often enough to create consistently moist soil – not overly wet, not bone-dry. To prevent diseases, keep foliage dry, especially if you must water late in the day.
Learn when it's safe to transplant seedlings. The first two leaves visible are usually "cotyledons," or seed leaves. Once the seedling grows several "true leaves," with a more typical rose leaf appearance, it is more likely to survive transplanting. It is also easier on plants if they are transplanted to a larger pot for a year or two, and then transplanted outside.
Remove the rose hips once ripe. The rose hips will start out small and green, then change color as they grow until they are completely red, orange, brown, or purple. You may pick them at this point, or wait until they are just beginning to dry out and wrinkle. Don't wait until they are fully dry and brown, as the seeds inside may have died by this point.
The Misting Method: As you get more sophisticated in your rose propagating methods you may eventually want to set up a misting bench. It can be an open-air bench or one enclosed in a greenhouse, or even a small misting box, similar to the one my husband Bob built for me. (Refer to "How We Made Our Misting Box," from Rose Ecstasy. You could choose to rig it up with a manual or an automatically-timed mister, whatever your time, money, or expertise will allow. I am fortunate to have a very handy guy for a husband, who is a good sport whenever I come up with these crazy project ideas.