Remove the rose hips once ripe. The rose hips will start out small and green, then change color as they grow until they are completely red, orange, brown, or purple. You may pick them at this point, or wait until they are just beginning to dry out and wrinkle. Don't wait until they are fully dry and brown, as the seeds inside may have died by this point.
Selecting a disease-resistant rose is the single most effective way to avoid problems and the need for chemicals. You might start by considering some of the old rose varieties, many of which have natural disease resistance. You can also look to many of the modern roses, which are now being bred for improved disease resistance. Hybrid teas are notoriously disease-prone, and seem to lure every insect pest from miles around. They can be difficult to grow without an arsenal of chemical dusts and sprays.

Prune the roses. Pruning roses keeps them both beautiful and healthy. The goal is to clear away crowded areas to open up the bush, which helps prevent rotting and disease. The pruning strategy differs according to the season, but the cut you make is always the same: prune just above a bud eyes, the areas where branches form. They look like small circular swells and are usually located above a set of mature leaves. Make a down-slanted cut on an outward-facing bud eye.

When pruning, be judicious. If you prune too hard in autumn, plants can be damaged beyond recovery. Instead, wait until spring, when plants begin to leaf out for the new season. (Roses are often not the earliest plants in the garden to respond to spring’s warming temperatures, so be patient.) Give the plant time to show its leaf buds then prune above that level.
Some people don't bother to take the time to do this, but others do. While the rose seeds are soaking, you will see that some sink to the bottom and some float on the top. The seeds that float are sometimes not viable, so you might want to throw them away. The rose seeds that sink are said to be the good ones, and are the ones to plant. There are pros and cons to this theory, and many rose hybridizers simply plant all the rose seeds that are harvested.   
So grandma had the right idea in the first place, and she really did know what she was doing. It has always been fun to start roses from cuttings. Some people get their kicks by going "rose rustling" in the deserted cemeteries of old and forgotten mining towns. Others just take a twig from their favorite rose and stick it into the ground in their backyard. There is nothing complicated nor scientific about taking cuttings of roses and rooting them to "start" a new plant. There are various ways of taking rose cuttings, so let's tell you how.
The next step when you grow roses from cuttings is to use a pencil or metal probe push down into the planting site soil to make a hole that is deep enough to plant the cutting up to about 50 percent of its overall length. Place the cutting that has been dipped into the rooting hormone into this hole. Lightly push the soil in around the cutting to finish the planting. Do the same thing for each cutting keeping them at least eight inches apart. Label each row of rose cuttings with the name of the mother rose bush it was taken from.

Taking rose cuttings can lead to a new crop of beautiful, successful roses. Like many other plants, it's important to choose a sunny spot for your rose cuttings that has moist soil. Cutting strong, healthy stems right above a set of leaves makes for great growing conditions, and dipping your cutting in a rooting hormone will help the roots take faster. By keeping your rose cuttings well hydrated, you'll have strong roots in no time.
Roses are flowering perennial plants prized for their beautiful flowers, which are made up of delicate and layered petals. One of the best ways to propagate new roses is to take a cutting from an existing plant and grow it into a whole new rose bush. When you grow roses from a cutting, you cut a stem from a healthy plant and root it in a growing medium so it grows into an independent plant of its own. However, you can also propagate roses by dividing an existing plant, but this requires a little more effort than with cuttings. To propagate by division, you have to dig up an entire rose bush, cut the root system in half, and replant the two halves as separate bushes.
I have successfully taken rose cuttings with both new and old wood. It is important to let the new stems sufficiently mature. The new wood is usually mature enough after the stem has just finished blooming. If you don't let the stem mature enough, then it usually becomes limp and will die before you can get it to root. I take cuttings from new rose stems in the spring right after the first bloom cycle. Then in early to late fall (in Southern California) I prefer to use more mature or old wood. When using old wood in the fall, I will remove the rose cuttings from the Mason jar, baggie, or mister, after only several weeks since it is cool enough then for them to root on their own as long as I water them daily.
Learn when it's safe to transplant seedlings. The first two leaves visible are usually "cotyledons," or seed leaves. Once the seedling grows several "true leaves," with a more typical rose leaf appearance, it is more likely to survive transplanting. It is also easier on plants if they are transplanted to a larger pot for a year or two, and then transplanted outside.[8]
Growing roses from seeds is not the fastest method for propagating roses but has several advantages. Roses from seeds take a little longer but then you end up developing a new set of varieties. Professional hybridisers select a new line of easy to grow and disease resistant rose to propagate. However, for you, each seedling will be a surprise when they finally bloom. It is like opening your birthday present when you were a kid. You never really knew what to expect! That is the same feeling seeing those little seedlings opens up for the first time.
To get the best success, yor rose seed will need a period of stratification (a cold period of about 6-12 weeks). Its a good idea to time this so that it coincides with when they would naturally start to grow in spring – probably around early March, depending on weather conditions. I would look to sowing them in late November/ December and popping them outdoors or if we have a mild winter then stick them in the fridge!
This is a fungus called black spot. Left untreated, it can cause all the leaves on your roses to turn yellow and fall off. It will also affect nearby plants, as it spreads by spores. Remove ALL INFECTED material and throw it away or burn it. Do NOT leave it on the ground as this fungus is very hardy. It can survive winter and travels very easily, even after being removed from the affected plant. Spray your plants regularly (bi-weekly) in the growing season with a good fungicide (I like the Bayer products). You can also add a little bit of dish soap and baking soda to a spray bottle with water and spray the entire plant.