Plant the seeds. Some store-bought seeds can be planted immediately. If you germinated your own seeds as described above, plant them as soon as they begin to sprout. Plant with the sprout pointed downward, as this is the root. Lightly cover them with soil, about 1/4 inch (6 mm) deep. Space seeds at least 2 inches (5 cm) apart to minimize competition.[5] 

I bought hybrid tea roses last year. Not long after the first blooms, we moved one because it was interfering with the sprinkler system. It looked unhappy at first, but continued to bloom throughout the season. This year, it does not have so much as one leaf, no new foliage whatsoever, however, there is still green inside the stem towards the base of the cane. Is it done for, or is there a chance it will come back in it's second rear?
Pick a sunny spot to plant your rose cuttings. Where you place your cuttings is especially important if you’re planning on growing them outdoors. Choose a spot that’s sunny but that’s not in direct sunlight — you don’t want them to dry out. Putting the rose cuttings in a pot or container is alright as well, just make sure the container is deep and wide enough for your rose cuttings to grow.[6]
The easiest way to begin experimenting with rose hybridizing, especially for the beginner, is to simply let some of your roses self-pollinate themselves, so they will "go to seed" and set hips. I have found that Playboy, Hurdy Gurdy, Peggy T and Fairhope are some of the easiest roses to set hips, and there are many others. Let the rose hips stay on the rose bushes at least four months before harvesting.   

Water: Roses require more water than most other landscape plantings, especially during the first year as the plant is getting its roots established. The best way to water your roses is with drip irrigation. It concentrates the water at the root zone where it is needed, and keeps the foliage dry to minimize disease problems. A good, thick layer of organic mulch will help conserve moisture, reduce weeds, and encourage healthy root growth. As the mulch breaks down, it will also add organic matter to the soil.

So grandma had the right idea in the first place, and she really did know what she was doing. It has always been fun to start roses from cuttings. Some people get their kicks by going "rose rustling" in the deserted cemeteries of old and forgotten mining towns. Others just take a twig from their favorite rose and stick it into the ground in their backyard. There is nothing complicated nor scientific about taking cuttings of roses and rooting them to "start" a new plant. There are various ways of taking rose cuttings, so let's tell you how.
Pruning: Dead, weak and sickly stems can lead to disease problems. Pruning these away will increase air circulation to the center of the plant and minimize fungus problems. Pruning also stimulates new growth, and allows you to shape the plant in a pleasing manner. Spent flowers should be removed during the growing season to encourage reblooming. Use a scissor-action pruner for the cleanest cuts.

After the rose seeds have soaked overnight, rinse them in a strainer and place them into the blender with at least a cup of plain purified water (making sure all seeds are covered), and turn it on for a few minutes. It usually doesn't chop up the seeds, but rather, it will clean off the pulp remaining from the rose hip, which would otherwise mold if left on the rose seed. You may see a few seeds chopped up, but those usually aren't viable anyway. Flush the rose seeds again through a strainer using fresh purified water.   

Grow your roses indoors, alternatively. You can also raise roses in a greenhouse. You’ll need containers that are at least 9 inches (22.9 cm) wide. Spread 1 to 2 inches (2.5 to 5.1 cm) of small pebbles at the bottom of each pot to ensure good drainage and fill each with halfway with well-draining soil. Plant the roses just beyond the graft point and then water well.[5]
Prepare a large hole. You'll need one for each rose bush you're planting. Use a garden spade or shovel to dig a hole 18 inches (45.7 cm) wide and 18 inches (45.7 cm) deep. The measurements don't have to be exact, but a hole this wide and deep will be suitable for most roses. Mix the soil you removed from the hole with compost, and use some of it to form a small mound in the base of the hole. Add some bonemeal or rose fertilizer.
Selecting a disease-resistant rose is the single most effective way to avoid problems and the need for chemicals. You might start by considering some of the old rose varieties, many of which have natural disease resistance. You can also look to many of the modern roses, which are now being bred for improved disease resistance. Hybrid teas are notoriously disease-prone, and seem to lure every insect pest from miles around. They can be difficult to grow without an arsenal of chemical dusts and sprays.
Pests and diseases: Prevention is the best way to avoid pest and disease problems. Start with disease-resistant varieties, keep plants in healthy condition (well fertilized and well watered), maintain good air circulation, keep foliage dry, and remove any diseased foliage or spent flowers. For Japanese beetle grubs, use beneficial nematodes or Milky Spore (Bacillus popilliae). Rose Rx is effective against scale, spidermites and aphids. For more information, see the Pest and Disease Finder.